Structure and function of macromolecules 15 hp

Program: Master programme in Biology
Level: Advanced level
Course code: 1BG349
Credits: 15 hp
More info: Course syllabus
Student portal: Schedule and course material

The overall goal of this course is to give students advanced knowledge of the relationship between the structure and function of biomolecules and to handle different tools used in structural bioinformatics. The student will also get good knowledge of current research and development of drugs directed against biological macromolecules. The student should after a completed course:

  • account for the basis of biological macromolecules' constitution and traits
  • explain structural mechanisms for how important biological processes take place and are controlled, for example catalysis, cell signalling and translation
  • account for the principles of the most important methods for structural analysis: X-ray crystallography, NMR spectroscopy and electron microscopy and analyse the quality of models produced by these methods
  • analyse structural details in macromolecules using a molecular graphics program
  • use databases with information of structure and function of macromolecules
  • use analyse, and critically evaluate results from methods to predict secondary - and tertiary structure of macromolecules
  • explain basic concepts and critically assess the relative strengths and weaknesses of fundamental approaches in computational biology
  • present and discuss scientific literature in the area of the course orally and in writing 

For more information, please contact:
Maria Selmer (maria.selmer@icm.uu.se)